SMART Therapy for Asthma in San Mateo, CA

Asthma treatment has changed significantly in recent years. SMART therapy is an approach that uses one specific type of combination inhaler for both daily asthma control and symptom relief. The inhaler contains an inhaled corticosteroid (ICS) to treat airway inflammation and formoterol, a bronchodilator that works quickly enough to relieve symptoms while also providing longer-lasting bronchodilation. For appropriate patients, SMART therapy can simplify treatment and reduce the risk of asthma exacerbations. Just as importantly, it provides anti-inflammatory medication at the time symptoms are occurring, rather than treating bronchospasm alone.

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What Is
SMART Therapy?

SMART stands for Single Maintenance and Reliever Therapy. It uses a single inhaler containing an inhaled corticosteroid (ICS) together with formoterol. The ICS treats the airway inflammation that is central to asthma, while formoterol relaxes the muscles surrounding the airways and works rapidly enough to provide symptom relief. The same ICS-formoterol inhaler is used as the patient’s regular maintenance treatment and, when needed, for additional symptom relief. This differs from the traditional approach in which a patient uses one inhaler every day for prevention and a separate albuterol-only inhaler for rescue. Not every combination asthma inhaler can be used for SMART therapy. Formoterol is important because it has a rapid onset of bronchodilation. The appropriate inhaler, maintenance dose, and maximum number of as-needed doses should be prescribed individually.

How SMART Therapy Works

Asthma symptoms result from both tightening of the muscles around the airways (bronchospasm) and inflammation inside the airways. SMART therapy is designed to address both.
Daily Maintenance
  • Take the prescribed maintenance dose as directed for ongoing asthma control.
  • The inhaled corticosteroid reduces airway inflammation.
  • Formoterol provides long-acting bronchodilation to help keep the airways open.
As-Needed Symptom Relief
  • Use additional inhalations as directed when asthma symptoms occur.
  • Formoterol provides rapid bronchodilation to help relieve wheezing, chest tightness, cough, and shortness of breath.
  • Each additional dose also delivers inhaled corticosteroid at a time when airway inflammation may be increasing.
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Who May Benefit From SMART Therapy?

SMART therapy may be appropriate for many patients who need regular controller treatment, particularly those who have had asthma exacerbations or remain inadequately controlled. Whether SMART is the best strategy depends on the patient’s age, symptoms, exacerbation history, current medications, inhaler technique, and overall level of asthma control. An evaluation may be particularly helpful for patients who:

  • Need regular controller medication for asthma.
  • Have frequent asthma symptoms or nighttime awakenings.
  • Have had asthma attacks, urgent-care or emergency visits, or courses of oral corticosteroids.
  • Are using symptom-relief medication frequently.
  • Remain limited by asthma during exercise, work, sleep, or daily activities.
  • Would benefit from simplifying a regimen that currently uses separate maintenance and rescue inhalers.
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What to Expect During Treatment

Consultation and Asthma Assessment
We review your symptoms, asthma history, previous exacerbations, current medications, rescue-inhaler use, possible triggers, and how asthma affects sleep, exercise, work, and daily life. We also confirm that the diagnosis and current treatment plan fit the pattern of your symptoms.
Lung Function and Related Testing
Spirometry and other lung-function testing may be used to assess airflow and help evaluate asthma control. Depending on the clinical situation, additional testing such as exhaled nitric oxide or allergy evaluation may be useful.
Prescription and Inhaler Training
If SMART therapy is appropriate, we select the inhaler and dosing plan and review exactly how to use it for both maintenance treatment and symptom relief. Proper inhaler technique is essential, so we make sure you understand how and when to use the medication.
Follow-Up and Adjustment
Asthma treatment should be reassessed periodically. Follow-up allows us to review symptom control, exacerbations, medication use, inhaler technique, side effects, and lung function when appropriate, and to adjust treatment as your needs change.

How Is SMART Different From a Traditional Rescue Inhaler?

Traditional rescue inhalers such as albuterol quickly relax the muscles surrounding the airways and can relieve wheezing, coughing, chest tightness, and shortness of breath. However, albuterol by itself does not treat the airway inflammation that is a central part of asthma.
With SMART therapy, the reliever inhaler contains both formoterol, which rapidly opens the airways, and an inhaled corticosteroid, which treats inflammation. This means that when symptoms increase and additional inhalations are needed, the patient receives both bronchodilator and anti-inflammatory treatment. Other newer rescue approaches can also provide an inhaled corticosteroid together with a bronchodilator. One example is Airsupra, which is discussed in the FAQs below. Airsupra is not SMART therapy because it is used as an as-needed rescue inhaler rather than as both maintenance and reliever treatment.

SMART Therapy and Different Types of Asthma

Asthma can present in different ways and may be influenced by different triggers. Patients may have allergic asthma, non-allergic asthma, adult-onset asthma, exercise-induced bronchoconstriction or exercise-related asthma symptoms, or asthma that worsens with seasonal allergens, respiratory infections, weather changes, or occupational exposures. Some patients have relatively infrequent symptoms, while others experience frequent symptoms or difficult-to-control asthma.
SMART therapy is not selected simply because a patient has one particular type of asthma. Whether it is appropriate depends on factors such as the patient’s age, frequency of symptoms, history of asthma exacerbations, current medications, inhaler technique, lung function, and overall level of asthma control. For patients with allergic asthma, identifying and treating relevant allergic triggers may also be an important part of achieving better asthma control. Likewise, patients whose symptoms occur with exercise, at work, or during certain seasons may benefit from identifying those patterns even when SMART therapy is part of the medication plan.

How We Measure Asthma Control

We assess the effectiveness of treatment using a combination of clinical and objective measures, which may include:
  • Frequency of daytime asthma symptoms.
  • Nighttime awakenings due to asthma.
  • How often symptom-relief medication is needed.
  • Asthma attacks and need for oral corticosteroids.
  • Urgent-care, emergency-department, or hospital visits.
  • Ability to exercise and participate in normal activities.
  • Asthma Control Test (ACT) scores or other validated symptom assessments.
  • Spirometry or other lung-function measurements when appropriate.
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Is SMART Therapy Right For You?

SMART therapy is often recommended for individuals with moderate to severe persistent asthma who struggle with symptoms despite conventional treatment or find managing multiple inhalers challenging.
Ideal Candidates Include:
  • Adults and adolescents requiring daily controller medication
  • Patients using rescue inhalers more than twice weekly
  • Those experiencing frequent symptoms despite current treatment
  • Individuals seeking simplified medication management
During a comprehensive consultation at our clinic, Dr. Andrew C. Engler and our expert team will evaluate your asthma type and severity, lung function, and lifestyle to determine whether SMART therapy is suitable for your needs.

Benefits of SMART Therapy

For appropriately selected patients, SMART therapy can provide several important advantages compared with treatment strategies that rely on a separate maintenance inhaler and an albuterol-only rescue inhaler.
  • Fewer severe asthma exacerbations.
  • Reduced need for oral corticosteroid treatment.
  • Fewer urgent-care, emergency-department, and hospital visits related to asthma.
  • Simplified medication routine with one inhaler
  • Enhanced ability to participate in physical activities
  • Better sleep quality without nighttime symptoms
  • Greater freedom in daily activities and exercise
  • Increased medication adherence due to convenience
  • Improved quality of life
The best treatment is the one that provides effective asthma control while minimizing exacerbations, medication burden, and side effects. SMART is an important option, but it is not the right approach for every patient.

Cost and Insurance Coverage

The cost of SMART therapy varies depending on the inhaler prescribed, insurance coverage, pharmacy benefits, and available formulary alternatives. Because coverage can differ considerably among plans, our team can help you understand the medication that has been recommended and the next steps if insurance coverage is a concern.
Insurance Coverage

The Allergy and Asthma Clinic accepts most major insurance plans for SMART therapy, including Aetna, Anthem, Blue Cross Blue Shield, Cigna, UnitedHealthcare, UMR, Guardian, Health Net, Medicare, Great-West Healthcare, MultiPlan, PHCS, SEQUOIA, and TRICARE.

For patients without insurance or incomplete coverage, we offer customized payment plans and flexible financing options. Our billing department provides detailed insurance verification and helps explore patient assistance programs for qualifying individuals.
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Personalized Asthma Care

Effective asthma care involves more than prescribing an inhaler. We evaluate how well your asthma is controlled, whether the diagnosis and current treatment make sense, how you are using your medications, and whether factors such as allergens, exercise, respiratory infections, or other conditions may be contributing to symptoms.
Our Expertise Includes:
  • Board-certified providers
  • Extensive experience in adult and pediatric allergy and asthma care
  • Personalized treatment plans tailored to your unique condition
  • Advanced lung function testing and same-day diagnostics
  • Both virtual and in-person appointment options
For some patients, SMART therapy can provide an effective and simpler approach to asthma management. Others may be better served by a different inhaler strategy or by additional treatment. Our goal is to help you understand your options and develop a practical treatment plan that provides the best possible asthma control.

Frequently Asked Questions (FAQs)

The formoterol component can begin relieving bronchospasm within minutes. The inhaled corticosteroid treats airway inflammation, and overall asthma control is assessed over time based on symptoms, medication use, exacerbations, activity level, and lung function when appropriate.

No. Airsupra is not SMART therapy, but it is based on a related treatment concept. Airsupra contains albuterol, which quickly opens narrowed airways, and budesonide, an inhaled corticosteroid (ICS) that treats airway inflammation. This means that when Airsupra is used for asthma symptoms, the patient receives treatment for both bronchospasm and inflammation rather than bronchodilation alone.

SMART therapy also treats both bronchospasm and inflammation, but it uses an ICS-formoterol inhaler. In SMART therapy, the same ICS-formoterol inhaler is used for both daily maintenance treatment and as-needed symptom relief.

Airsupra is used as an as-needed rescue inhaler, not as the daily maintenance inhaler, so it is not considered SMART therapy. Which approach is most appropriate depends on factors such as asthma severity, current medications, history of asthma attacks, and how well the asthma is controlled.

The terms are closely related. SMART stands for Single Maintenance and Reliever Therapy. International asthma guidelines commonly use the term MART, meaning Maintenance and Reliever Therapy. Both describe using an appropriate ICS-formoterol inhaler for maintenance treatment and symptom relief.

SMART therapy can be appropriate for some children and adolescents, but the recommended inhaler, dose, and age range depend on the individual patient and the treatment guideline being followed. A pediatric asthma regimen should be selected and monitored by a clinician familiar with the child’s asthma history and inhaler use.

Follow the dosing instructions provided with your treatment plan. If you are frequently missing maintenance doses or are unsure how to use the inhaler after a missed dose, contact your clinician rather than changing the regimen on your own.

Yes, some patients need additional asthma treatment. However, medications should be reviewed carefully so that bronchodilators and inhaled corticosteroids are not unintentionally duplicated and the overall regimen remains safe and understandable.

In SMART therapy, the prescribed ICS-formoterol inhaler is used for symptom relief as well as maintenance treatment. Whether you should also carry or use a separate albuterol inhaler depends on your individual treatment plan and should be clarified with your clinician.

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First and foremost let me start by saying that these people did one hell of a job figuring out my sinus problems. When I first arrived there, I explained what was going on with me having excessive inflammation in the sinus…after they tested me, I found out that I was being exposed to dust mites which gave me a strong reaction. I followed the doctors guides lines in terms of cleaning my room and ever since, my sinus inflammation went away for good and now I have a healthy sinus. Thank you for everything.

- Johnathon T
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Dr. Engler is great and his staff, both medical and administrative, are wonderful. Dr. Engler is competent, caring, and listens better than any doctor I’ve ever had, constantly and patiently asking if I have any more questions. The staff is great. The nurses are very friendly and helpful. The desk staff is the same. I have been going here over a year and have always received caring and competent treatment. I highly recommend them.
- Tom B
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Hands down the best place to go for Allergies and Asthma. The staff is incredibly kind and caring and so professional and helpful. I’ve been going here for over 30 years and they have gone out of their way countless times to make sure that I was well-cared-for. The nurses are excellent and always make sure to ask how my family is doing not to mention that they give the most painless allergy shots around. They remember little details about me and always make sure to give me a lollipop for my son, even when he’s not with me. Brooke is a great diagnostician and listener and each time I have an appointment with her, I always leave feeling better. The same is true for Dr. Engler.

My 10 year old son also has allergies and asthma and the staff makes sure that he feels well taken care of and comfortable, despite his having Autism and ADHD. He actually looks forward to going there with me, whether it be for my allergy shots or even when he needed allergy skin testing. When you’re a patient at the Allergy and Asthma clinic, you are treated as if you are the only patient they have, even when the waiting room is full. Dr. Engler has hired truly excellent staff, from the front desk people to the nurses and medical assistants. If you have allergies and/or asthma and you live on the Peninsula or even in the city, I highly recommend that you visit the Allergy and Asthma Clinic. They are truly amazing and will make you feel so much better.

-Sandi S.
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I had an amazing experience at this clinic. Dr. Engler and the staff were all extremely welcoming, warm, and thorough in their various lanes of work from the front desk to billing to the assistants to Dr. Engler himself.
One thing I wish I knew before coming in was that the food test covers 80 allergens, and the environmental test covers 80 allergens meaning if you want to do both you need to come two separate days. This is kind of a hassle but definitely worth it since you’ll be tested for 160 allergens whereas most clinics only test 80 total.
Through the tests I figured out what I was allergic to and was advised to use an over the counter medication which has drastically helped and eliminated the symptoms I was experiencing. Dr. Engler also covered all the things I needed to do to reduce my symptoms via my lifestyle which was super helpful with my symptom reduction as well. I’d highly recommend this clinic! Insurance covered the tests and visits. (I have anthem blue cross)
-Christina L
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I’ve been a patient at The Allergy and Asthma Clinic for over 12 years, and I can’t speak highly enough of the care I’ve received. Growing up with severe pollen allergies, I’ve been on and off allergy shots for years, and this clinic has truly been a lifesaver for me.
From the moment you walk in, you’re treated like family. The staff is incredibly kind, caring, and genuinely invested in your well-being. I have never had a negative experience with anyone here; everyone is consistently friendly and supportive.
Dr. Engler is exceptional! He has a remarkable ability to quickly and effectively address any situation. His expertise and compassionate approach have made a significant difference in managing my allergies.
If you’re struggling with allergies or asthma, this is the place to go. I wholeheartedly recommend The Allergy and Asthma Clinic to anyone seeking top-notch care.
-Trevor C